At least two people have lost their lives after a fatal shooting and a house fire also left three children missing in Arizona.
The Tuscon Police Department said a gunman was shot after he killed a neighbor, injured three first responders and a bystander in a deadly rampage, per ABC News.
The charred remains of another unidentified person were found inside the home and "two or three" children who lived there remain missing.
Police chief Chris Magnus said during a press conference that the "horrific" incident took place in three different locations in the downtown area on Sunday, July 19.
Watch a full news report about the incident below:Dispatchers first received a 911 call informing them of a house fire on the 2100 block of East Irene Vista.
A second call was received around the same time about a medical emergency at the nearby Quincy Douglas Park.
Emergency services were greeted by a 35-year-old man at the scene who pulled up in a silver SUV alongside the ambulance before opening fire.
The ambulance driver was shot in the head and remains in a critical condition, per The Sun.
A female EMT who was sitting in the passenger's seat, meanwhile, was shot in the arm, but she is in a stable condition.
The gunman fled the scene in his car, and emergency assistance was called for by the female EMT, who went on to describe the gunman.
As the gunman fled the scene, he encountered an eight-year veteran of the police department, Magnus revealed.
"As one of the officers drives up the street, he sees the suspect in the vehicle and the suspect sees him," he said. "The suspect then attempted to ram the officer... disabling the police car."
The suspect opened fire on the officer when he stepped out of his car, and this fire was returned, which is what resulted in his critical injury.
He was taken into custody before being transported to a hospital, where, the Sun reports, he remains critically injured.
The "badly charred" remains of an unknown victim were found at the home, and it was then discovered that three children who lived there are missing.
Police are now reaching out to family, friends, and neighbors in a bid to find them.
Magnus described the situation as "extremely complicated."
"This is highly tragic, really horrific with many unknowns," he continued.
"This is a really horrific incident and our hearts go out obviously to those who are concerned about their loved ones with more serious injuries. We just don't know."
