Ozempic and other GLP-1 medications have boomed in recent years after it was discovered that they can aid weight loss as well as helping control blood sugar.
While they were first developed to treat type-2 diabetes, their weight-loss benefits have meant that they are increasingly used for this purpose instead.
Though some people see it as a holy grail to being able to shift pounds that were seemingly impossible to budge before, the medication isn't without its side effects.
A simulation video made by Zack D Film has shown the horrific side-effects some people can experience when taking GLP-1s.
Ozempic can cause several side-effects. Credit: Mario Tama/Getty Images
In the clip, he first explained how the drugs work: "Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite.
"It also stabilizes your blood sugar, stopping sudden cravings. Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal. This causes you to lose weight as you eat less."
He revealed some of the side effects that many people experience, adding: "But it can make some people feel sick and even give them diarrhea."
According to WebMD, there are other common potential side-effects people can experience, including nausea, vomiting, diarrhea, stomach pain, and constipation.
Some users can also experience pancreatitis, an inflammation of the pancreas which causes vomiting or severe pain in the upper part of your belly that travels to your back.
Other less common side-effect include issues with the gallbladder, low blood sugar, severe stomach pains, vision changes, and there is even the potential for thyroid tumors.
It goes without saying that using Ozempic and other GLP-1s should never be as a quick fix to lose a few pounds, unless you have been prescribed it by a doctor.
It is primarily used to treat type 2 diabetes and to lower the risk of a heart attack, stroke, or death in people who also have heart disease, as well as to help lower blood sugar levels in people with type 2 diabetes.
Ozempic and other GLP-1s are usually administered by injection once a week, with the dose being gradually increased over time.
As well as the immediate physical side-effects, some users are noting longer-term changes such as Ozempic face and Ozempic butt - where the skin or the buttocks appear to sag due to the rapid loss of fat from beneath.
Ozempic might be all the rage among celebrities and social media users trying to slim down fast — but a viral simulation has revealed what the weight-loss drug really does to your body, and it has raised some eyebrows.
Originally designed for people with Type-2 diabetes, Ozempic (semaglutide) has exploded in popularity thanks to its unexpected weight-loss benefits.
But what was meant to be a prescription-only treatment to help regulate blood sugar is now being used off-label by people desperate to shed pounds — despite the long list of side effects.
Users of Ozempic are using it to lose weight. Credit: Mario Tama/Getty Images
What actually happens to your body on Ozempic?
YouTuber Zack D. Films recently broke down the process in a now-viral simulation video, and let’s just say the final scene is not for the faint-hearted.
“Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite,” he explains in the clip. “It also stabilises your blood sugar, stopping sudden cravings. Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal. This causes you to lose weight as you eat less.
"But it can make some people feel sick and even give them diarrhoea.”
In fact, the simulation ends with a disturbingly realistic image of an Ozempic user soiling themselves — sparking horror across the comment section.
“Last scene was NOT NEEDED Zack,” one person wrote. Another added: “Watching Zack’s animations make me lose my appetite more than Ozempic.” And a third said: “Zack’s never ending love for poop or diarrhea never ends.”
It’s not a weight loss drug — officially
Despite its cult following as a miracle slimming shot, the Ozempic website is very clear: it “is not a weight loss drug.”
Instead, it’s an injectable prescription medication for adults with Type-2 diabetes, meant to be used “along with diet and exercise to improve blood sugar (glucose).”
It’s also used to “reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease,” and to help lower the risk of kidney disease and cardiovascular-related death in people with chronic conditions.
So what are the actual side effects?
While Ozempic might make you lose weight, it can also have an unexpected impact on your body in several ways, per Healthline. The most common side effects include:
Nausea
Diarrhoea
Stomach pain
Vomiting
Constipation
Other milder — but still unpleasant — symptoms may include:
Burping
Dizziness
Headaches
Fatigue
Indigestion or acid reflux
Gassiness
A change in how things taste
Injection site reactions like discoloration or discomfort
A slight rise in heart rate
And then there are the more serious risks: thyroid tumors, pancreatitis, changes in vision, severe stomach issues, dehydration-related kidney problems, allergic reactions, low blood sugar, and gallbladder problems such as gallstones or cholecystitis.
Celebs speak out: “I was like, vomiting”
While many stars have jumped on the Ozempic bandwagon, some have spoken candidly about how bad the side effects got.
Ozempic is approved to treat type 2 diabetes. Credit: Steve Christo - Corbis/Getty
Amy Schumer didn’t hold back: “I was like, vomiting — and then you have no energy,” she revealed, saying the drug left her “bedridden.” While others she knew had no issues, she personally switched to Mounjaro and called it “great.”
Jeremy Clarkson compared the experience to “living a minibar existence.”
“My body lost the ability to deal with gluttony but once the initial enthusiasm had worn off, my mind still wanted to breakfast on Cadbury Fruit & Nut,” he wrote in The Times. “This meant I was sick a lot.”
Stephen Fry said the drug initially made him “not want to eat” — but that quickly turned. “And I started feeling sicker and sicker and sicker,” he said on the River Café Table 4 podcast. “I was literally throwing up four, five times a day and I thought, 'I can't do this'. So that's it.”
“I tried Ozempic almost three years ago and I was like, bedridden,” she said. “I was like, vomiting — and then you have no energy. But other people take it and they’re all good.”
Undeterred, Schumer gave similar drugs another shot and recently revealed in an Instagram video that she’s having a better experience this time around with Mounjaro.
“Three years ago, I tried Wegovy,” she shared. “I was puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever.”
She went on to describe her virtual health referral through the online midlife clinic Midi Health, and revealed she’s also been prescribed estrogen and progesterone to manage perimenopause symptoms.
“So that’s been great and Mounjaro’s been great,” she said.
Though she acknowledged that Mounjaro isn’t fully covered by insurance in the U.S. unless you have diabetes or severe obesity, she joked: “Which most of the internet thinks I have, but I’m having a really good experience with it."
How it compares to Mounjaro
In the UK, Ozempic isn’t even available for weight-loss use.
The NHS currently only prescribes it for diabetes treatment. Brits looking for weight loss support are instead turning to Mounjaro, which contains a different active ingredient, tirzepatide.
Mounjaro is approved for weight loss, while Ozempic is not. And there are key differences. Ozempic has a maximum dosage of 2mg, whereas Mounjaro can go up to 15mg. Both drugs help regulate blood sugar and reduce appetite, but Mounjaro follows a different dosage schedule and is officially backed for slimming down.
At the end of the day, if you're hoping to lose weight by using one of these options, make sure you're fully aware of the risks and potential side effects.
Featured image credit: Steve Christo - Corbis/GettyYoutube/ZackDFilms
A simulation has revealed what happens to your body when you take Ozempic, as more and more people are using the drug.
Ozempic is approved to treat type 2 diabetes. Credit: Steve Christo - Corbis/Getty
While Ozempic has blown up on social media for its dramatic slimming effects, it’s worth remembering that the drug wasn’t actually designed to help people fit into smaller jeans.
According to the official Ozempic website, it "is not a weight loss drug" and is actually "a medicine for adults with type 2 diabetes."
Ozempic is an injectable prescription medication that's meant to be used “along with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes.”
It’s also prescribed to “reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease.”
But the real magic — or misery — happens because of how it interacts with the body.
The drug curbs your appetite, makes you feel full faster, and slows down digestion, which leads to fewer calories consumed. Pair that with exercise and voilà — a calorie deficit, and you start shedding pounds.
Still, that doesn’t mean the ride is smooth.
Users of Ozempic are using it to lose weight. Credit: Mario Tama/Getty Images
That's where Zack D. Films comes in.
He recently released a graphic simulation video showing exactly what Ozempic does once it’s in your body — and it’s going viral for all the wrong (and right?) reasons.
"Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite," Zack explains in the video.
"It also stabilises your blood sugar, stopping sudden cravings. Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal.
"This causes you to lose weight as you eat less. But it can make some people feel sick and even give them diarrhoea."
The final scene of Zack’s simulation takes a turn — showing a disturbingly realistic visual of the Ozempic user soiling themselves.
Lovely.
People, as usual, were pretty disgusted.
"Last scene was NOT NEEDED Zack," one person wrote, as a second added: "Watching Zack’s animations make me lose my appetite more than Ozempic."
A third person added: "Zack’s never ending love for poop or diarrhea never ends."
As Ozempic becomes more popular, even celebrities have opened up about using it.
“I tried Ozempic almost three years ago and I was like, bedridden,” she said. “I was like, vomiting — and then you have no energy. But other people take it and they’re all good.”
Undeterred, Schumer gave similar drugs another shot and recently revealed in an Instagram video that she’s having a better experience this time around with Mounjaro.
“Three years ago, I tried Wegovy,” she shared. “I was puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever.”
She went on to describe her virtual health referral through the online midlife clinic Midi Health, and revealed she’s also been prescribed estrogen and progesterone to manage perimenopause symptoms.
“So that’s been great and Mounjaro’s been great,” she said.
Though she acknowledged that Mounjaro isn’t fully covered by insurance in the U.S. unless you have diabetes or severe obesity, she joked: “Which most of the internet thinks I have, but I’m having a really good experience with it."
Featured image credit: Steve Christo - Corbis/Getty
Ozempic has gained massive popularity as a weight loss treatment, but health experts and legal professionals are raising concerns over some of its severe side effects.
While many users focus on the drug's ability to help shed pounds, others are experiencing significant gastrointestinal complications.
A recent online video highlights a visual representation of what can go wrong inside the body when taking this medication.
In a YouTube video posted by the official YouTube page for Dolman Law Group, attorney Stanley Gipe speaks about the Ozempic side effects people don’t often talk about.
Ozempic has gained massive popularity as a weight loss treatment. Credit: Steve Christo - Corbis / Getty
In the video, he can be seen explaining some of the negative effects of Ozempic, with the video intermittently cutting to a simulation showing what happens to food in the digestive system when taking Ozempic.
The visual presentation demonstrates how food can grind to a complete halt inside the stomach, showing the potential medical risks associated with severe gastrointestinal slowdowns.
During the clip, Gipe breaks down the primary mechanism of the drug and why it leads to severe complications for certain patients.
Gipe says, "This popular weight loss drug is causing serious damage to your body, and you probably don't even know it.
"Ozempic is one of these drugs that slows down digestion. So people are more satiated, they feel more full, and they don't need to eat as often.
"The problem is when it works too well, the food stops moving. You get an extreme form of constipation. This can lead to all sorts of medical issues.
I just don't think the doctors are getting full disclosure about all the dangerous nature of the drugs they're prescribing."
Understanding the mechanics of GLP-1 medications
Medications like Ozempic mimic Glucagon-like peptide-1, a hormone involved in regulating appetite. While natural bursts of this hormone last only a few minutes after eating, GLP-1 medications create a much stronger and longer-lasting effect.
According to medical experts, this sustained activity slows down gastric emptying significantly, which keeps individuals feeling full for extended periods.
However, when gastric emptying slows down excessively, patients can face severe complications. Medical dietitians note that nausea, constipation, diarrhea, bloating, and vomiting are well-recognized side effects of these drugs.
When food remains in the stomach and upper gastrointestinal tract for longer than normal, it gives the gut microbiome more opportunity to ferment partially digested food, which can lead to unpleasant gases and severe discomfort.
Managing risks associated with Ozempic
Healthcare professionals emphasize that preparing the digestive system before starting GLP-1 medications is crucial for reducing risks.
Pre-existing conditions like reflux or constipation can worsen once treatment begins. Experts advise patients to gradually increase their fiber intake, maintain proper hydration, and stop eating immediately upon feeling full to prevent severe gastrointestinal distress.
In addition to digestive issues, doctors warn about potential nutrient deficiencies caused by substantial reductions in food intake. Patients on GLP-1 drugs may miss out on essential nutrients such as vitamin D, vitamin B12, iron, calcium, and protein if their overall diet quality is poor.
Medical experts recommend that anyone taking these medications pair their treatment with balanced nutrition and regular physical activity to safeguard overall health.
The rise in popularity of weight loss medications like Ozempic has sparked a lot of buzz - and not all of it is positive.
While many are flocking to the injection for its potential benefits, some side effects are causing users to second guess their decision.
Among the more bizarre reactions to the glucagon-like peptide-1 (GLP-1) injections is something users have started calling "Ozempic poo." And as you can imagine, it’s not exactly a pleasant experience.
What is Ozempic Poo?
As the name might suggest, "Ozempic poo" isn’t something you'd want to experience. Alongside other strange side effects tied to GLP-1 injections, such as "Ozempic penis" and "Ozempic teeth," "Ozempic poo" has been described as the most unpleasant consequence, per Business Insider.
This particular side effect doesn’t involve any magical transformations like turning your bathroom trips into piles of gold.
In fact, it’s the complete opposite - leading to some, unfortunately, dealing with unexpected and uncontrollable bowel movements.
While President Donald Trump played a significant role in bringing weight loss drugs like Ozempic into the spotlight, the surge in their use has also made the side effects more noticeable.
As the price of these injections drops and more alternatives hit the market, people are increasingly using them in hopes of shedding pounds or potentially reversing signs of liver damage.
However, it’s not all good news, as other studies have linked GLP-1 drugs to more serious issues like pancreatitis.
Ozempic could impact bowel movements. Credit: Antonio Hugo Photo / Getty
Over on Reddit, one user shared their frustrations, asking: “Any advice for not s**tting in the bed while sleep?”
The original poster (OP) explained that they had been struggling with this uncomfortable issue for months, calling it "the most annoying side effect." And honestly, who could blame them?
The Reddit thread quickly became a place for others to share similar experiences.
One commenter offered some advice: "That’s an extreme side effect. You should talk to your doctor. Do not eat any greasy foods or complicated carbohydrates. Eat small amounts. Don’t eat after seven. You can become extremely dehydrated. Good luck."
Another user expressed a mix of excitement and apprehension: “This week was my third shot. Things I’m looking forward to: 1. Lowering my A1C. Second week on this subreddit. Things I’m not looking forward to: 1. Having my hair fall out. 2. S**tting the bed. In no particular order.”
However, not everyone shares the same experience. Some reported the opposite problem, experiencing constipation instead of diarrhea.
One user shared: “Yeah I’m s**tting rocks so I can’t relate.” Meanwhile, others suggested more drastic solutions, with one person even recommending diapers to manage the issue.
The Science Behind Ozempic Poo
If you’re wondering what exactly causes this uncomfortable side effect, Dr. Daniel Rosen, a weight loss doctor, took to TikTok to provide an explanation.
According to Dr. Rosen, the gastrocolic reflex could be responsible. "When you eat a large meal, there's something called the gastrocolic reflex, where the stretch in the top of the stomach alerts the very end of the colon and rectum to empty," he explained.
GLP-1 medications like Ozempic and Wegovy, which are designed to suppress appetite and help with weight loss, can "trick your brain into thinking that food has arrived at the end of the intestines."
This may explain why some users experience the urgent need to go to the bathroom unexpectedly, leading to the dreaded "Ozempic poo."
The popularity of Ozempic, a medication originally developed for managing type 2 diabetes, has surged as it has gained a reputation for helping people lose weight. However, this injectable drug has its fair share of side effects, and not all of them are pleasant.
As more people turn to GLP-1 drugs like Ozempic for weight loss, the side effects are becoming more apparent. Among the most unsettling of these side effects is what has come to be known as "Ozempic poop." It's a term coined by users who have experienced gut-wrenching issues with their bowel movements while on the medication.
For some, Ozempic's effects on digestion have caused unexpected and uncontrollable bowel movements. While some are dealing with the opposite problem - constipation -others are facing the issue of frequent, urgent trips to the bathroom, sometimes with no warning at all.
Understanding this phenomenon has led to countless discussions among users trying to make sense of the issue. So, what exactly is "Ozempic poop," and why is it happening?
What is Ozempic poo?
As the name suggests, "Ozempic poo" refers to an unpleasant side effect tied to using the medication. According to Business Insider, "Ozempic poo" is considered one of the worst side effects of GLP-1 injections like Ozempic, with users describing it as a form of diarrhea that hits unexpectedly and often. The condition is not a magical transformation - unfortunately, it's more about uncontrollable, inconvenient bowel movements that leave users scrambling for solutions.
This is not an isolated issue, as many individuals have started discussing their experiences on social media platforms like Reddit, sharing their struggles and seeking advice from others who have been through similar situations. Despite the popularity of Ozempic, its side effects, including gastrointestinal issues, have prompted some users to reconsider their use of the medication.
Credit: Westend61/Getty
How to check if you have Ozempic poop
If you're taking Ozempic and suspect that you're experiencing "Ozempic poop," pay attention to the frequency and urgency of your bowel movements. The key signs to look out for are sudden, uncontrollable urges to go to the bathroom, especially after meals. This could be accompanied by diarrhea or a general feeling of discomfort in your stomach or intestines.
To check if the issue is indeed related to the medication, track your bowel movements and note any patterns that arise after taking your Ozempic dose. If you're noticing a consistent link between the injections and these digestive issues, it's a sign that the medication could be the culprit.
Additionally, if your bowel issues are causing significant distress or interfering with your daily life, it's a good idea to consult with your healthcare provider. They may be able to adjust your dosage or suggest ways to manage the side effects.
Ozempic is approved to treat type 2 diabetes. Credit: Steve Christo - Corbis/Getty
Users share their Ozempic poop nightmares
The rise of "Ozempic poop" has led to many users speaking out about their experiences, often with a mix of frustration and humor. One user on Reddit described their situation in a post: “Any advice for not s**tting in the bed while sleep?” This unfortunate experience of dealing with uncontrollable bowel movements even during sleep is one of the more troubling aspects of the medication for some users.
In response, others on Reddit have shared advice, with one user recommending avoiding greasy foods and eating smaller portions to prevent dehydration and further digestive distress. Some users have expressed a sense of dread, sharing their worries about side effects like hair loss and, of course, "s**tting the bed." Yet, not everyone experiences the same issues; some users report the opposite problem, struggling with constipation instead.
The science behind Ozempic poo
To better understand why this side effect occurs, Dr. Daniel Rosen, a weight loss doctor, provided an explanation on TikTok. According to Dr. Rosen, the gastrocolic reflex could play a role in causing these sudden urges to go to the bathroom.
He explains that when a person eats a large meal, the stretch in the stomach sends signals to the colon and rectum, prompting them to empty. GLP-1 medications like Ozempic can "trick your brain into thinking that food has arrived at the end of the intestines," triggering the gastrocolic reflex prematurely and leading to urgent bowel movements.
While the idea of dealing with "Ozempic poo" is unsettling, understanding the science behind it may help users manage the side effects more effectively. If you're experiencing this issue, it's essential to talk to your healthcare provider, as they may offer strategies to minimize the discomfort associated with this particular side effect.
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