Ozempic might be all the rage among celebrities and social media users trying to slim down fast — but a viral simulation has revealed what the weight-loss drug really does to your body, and it has raised some eyebrows.

Originally designed for people with Type-2 diabetes, Ozempic (semaglutide) has exploded in popularity thanks to its unexpected weight-loss benefits.

But what was meant to be a prescription-only treatment to help regulate blood sugar is now being used off-label by people desperate to shed pounds — despite the long list of side effects.

What actually happens to your body on Ozempic?

YouTuber Zack D. Films recently broke down the process in a now-viral simulation video, and let’s just say the final scene is not for the faint-hearted.

“Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite,” he explains in the clip. “It also stabilises your blood sugar, stopping sudden cravings. Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal. This causes you to lose weight as you eat less.

"But it can make some people feel sick and even give them diarrhoea.”

In fact, the simulation ends with a disturbingly realistic image of an Ozempic user soiling themselves — sparking horror across the comment section.

“Last scene was NOT NEEDED Zack,” one person wrote. Another added: “Watching Zack’s animations make me lose my appetite more than Ozempic.” And a third said: “Zack’s never ending love for poop or diarrhea never ends.”

It’s not a weight loss drug — officially

Despite its cult following as a miracle slimming shot, the Ozempic website is very clear: it “is not a weight loss drug.”

Instead, it’s an injectable prescription medication for adults with Type-2 diabetes, meant to be used “along with diet and exercise to improve blood sugar (glucose).”

It’s also used to “reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease,” and to help lower the risk of kidney disease and cardiovascular-related death in people with chronic conditions.

So what are the actual side effects?

While Ozempic might make you lose weight, it can also have an unexpected impact on your body in several ways, per Healthline. The most common side effects include:

1. Nausea
2. Diarrhoea
3. Stomach pain
4. Vomiting
5. Constipation

Other milder — but still unpleasant — symptoms may include:

1. Burping
2. Dizziness
3. Headaches
4. Fatigue
5. Indigestion or acid reflux
6. Gassiness
7. A change in how things taste
8. Injection site reactions like discoloration or discomfort
9. A slight rise in heart rate

And then there are the more serious risks: thyroid tumors, pancreatitis, changes in vision, severe stomach issues, dehydration-related kidney problems, allergic reactions, low blood sugar, and gallbladder problems such as gallstones or cholecystitis.

Celebs speak out: “I was like, vomiting”

While many stars have jumped on the Ozempic bandwagon, some have spoken candidly about how bad the side effects got.

Amy Schumer didn’t hold back: “I was like, vomiting — and then you have no energy,” she revealed, saying the drug left her “bedridden.” While others she knew had no issues, she personally switched to Mounjaro and called it “great.”

Jeremy Clarkson compared the experience to “living a minibar existence.”

“My body lost the ability to deal with gluttony but once the initial enthusiasm had worn off, my mind still wanted to breakfast on Cadbury Fruit & Nut,” he wrote in The Times. “This meant I was sick a lot.”

Stephen Fry said the drug initially made him “not want to eat” — but that quickly turned. “And I started feeling sicker and sicker and sicker,” he said on the River Café Table 4 podcast. “I was literally throwing up four, five times a day and I thought, 'I can't do this'. So that's it.”

On The Howard Stern Show, Amy Schumer admitted to trying the drug, but said it left her in rough shape.

“I tried Ozempic almost three years ago and I was like, bedridden,” she said. “I was like, vomiting — and then you have no energy. But other people take it and they’re all good.”

Undeterred, Schumer gave similar drugs another shot and recently revealed in an Instagram video that she’s having a better experience this time around with Mounjaro.

“Three years ago, I tried Wegovy,” she shared. “I was puking, I couldn’t handle it. I don’t know if they’ve changed the formula, whatever.”

She went on to describe her virtual health referral through the online midlife clinic Midi Health, and revealed she’s also been prescribed estrogen and progesterone to manage perimenopause symptoms.

“So that’s been great and Mounjaro’s been great,” she said.

Though she acknowledged that Mounjaro isn’t fully covered by insurance in the U.S. unless you have diabetes or severe obesity, she joked: “Which most of the internet thinks I have, but I’m having a really good experience with it."

How it compares to Mounjaro

In the UK, Ozempic isn’t even available for weight-loss use.

The NHS currently only prescribes it for diabetes treatment. Brits looking for weight loss support are instead turning to Mounjaro, which contains a different active ingredient, tirzepatide.

Mounjaro is approved for weight loss, while Ozempic is not. And there are key differences. Ozempic has a maximum dosage of 2mg, whereas Mounjaro can go up to 15mg. Both drugs help regulate blood sugar and reduce appetite, but Mounjaro follows a different dosage schedule and is officially backed for slimming down.

At the end of the day, if you're hoping to lose weight by using one of these options, make sure you're fully aware of the risks and potential side effects.

Featured image credit: Steve Christo - Corbis/GettyYoutube/ZackDFilms

Ozempic and other GLP-1 medications have boomed in recent years after it was discovered that they can aid weight loss as well as helping control blood sugar.

While they were first developed to treat type-2 diabetes, their weight-loss benefits have meant that they are increasingly used for this purpose instead.

Though some people see it as a holy grail to being able to shift pounds that were seemingly impossible to budge before, the medication isn't without its side effects.

A simulation video made by Zack D Film has shown the horrific side-effects some people can experience when taking GLP-1s.

Ozempic can cause several side-effects. Credit: Mario Tama/Getty Images

In the clip, he first explained how the drugs work: "Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite.

"It also stabilizes your blood sugar, stopping sudden cravings. Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal. This causes you to lose weight as you eat less."

He revealed some of the side effects that many people experience, adding: "But it can make some people feel sick and even give them diarrhea."

According to WebMD, there are other common potential side-effects people can experience, including nausea, vomiting, diarrhea, stomach pain, and constipation.

Some users can also experience pancreatitis, an inflammation of the pancreas which causes vomiting or severe pain in the upper part of your belly that travels to your back.

Other less common side-effect include issues with the gallbladder, low blood sugar, severe stomach pains, vision changes, and there is even the potential for thyroid tumors.

It goes without saying that using Ozempic and other GLP-1s should never be as a quick fix to lose a few pounds, unless you have been prescribed it by a doctor.

It is primarily used to treat type 2 diabetes and to lower the risk of a heart attack, stroke, or death in people who also have heart disease, as well as to help lower blood sugar levels in people with type 2 diabetes.

Ozempic and other GLP-1s are usually administered by injection once a week, with the dose being gradually increased over time.

As well as the immediate physical side-effects, some users are noting longer-term changes such as Ozempic face and Ozempic butt - where the skin or the buttocks appear to sag due to the rapid loss of fat from beneath.

Featured image credit: Mario Tama/Getty Images

As if we as a species did not have enough body hang-ups to worry about, the latest thing stressing some people out before bikini season is 'Ozempic butt'.

The relatively new phenomenon has come about since the rise in popularity of the diabetes drug Ozemic (semaglutide), which came into circulation to help people with type 2 diabetes lose weight by curbing their appetite.

The drug is injected once a week and works by helping the pancreas make more insulin, decreasing the amount of glucose made by the liver, and slowing the rate food passes through the body, making the patient feel full longer, according to Drugs.com.

However, many people who have been using Ozempic and similar semaglutide injections for weight loss have discovered one side-effect they weren't prepared for - Ozempic butt.

Users of Ozempic are noticing an unwanted side effect on their butts. Credit: Mario Tama/Getty Images

Alongside the weight loss achieved by taking Ozempic, many patients are finding it has had a less-than-desirable effect on their backsides, leaving them flat and droopy.

Jess Loren, 39, who lost over 75lb after starting Ozempic when she weighed 227lb, told the New York Post of her experience, explaining: "My dad said, 'You don’t have a butt anymore.'

"I try on bathing suits and I’ve got 'ghost a**,' or what people online call 'Ozempic butt.'"

While there are many official side-effects that can occur from Ozempic, such as nausea or vomiting, and even pancreatitis among others, 'Ozempic butt' is not officially listed as a side-effect in the medication's guidelines.

However, rapid weight loss can often cause formerly full areas of the body to sag - and it's not just the butts that are being affected.

Celebrities such as Jessica Simpson and Scott Disick have been accused of ending up with 'Ozempic face', which is where the rapid weight loss causes the cheeks to appear gaunt and the eyes to sink in.

Dr. Iman Saleh, Northwell Health Clinical Assistant Professor, OB/GYN Department and Director of Obesity Medicine, South Shore University Hospital, told People: "The faces are saggy, they lose their fat content in their face, there are increased wrinkles.

"Some people look a little bit more aged. People have noticed that there's more hollowing around their eyes because of the loss of the texture or the fat content that is in the face."

People are finding they're losing the shape in their buttocks due to the rapid weight loss. Credit: LumiNola/Getty Images

'Ozempic face' and 'Ozempic butt' is also not down to the drug itself, but the method of weight loss, with rapid and significant changes in weight causing the skin to sag, which can only be avoided by losing weight slowly rather than all at once.

Others have also reported the same effect on their cleavage, with 'Ozempic breasts' also becoming a side-effect of the fast weight loss these medications can sometimes create.

Saleh explained: "People who have had weight-loss surgeries will have the same effect. So, it's not the medications itself that are causing this.

"It's the rapid weight loss that is occurring with the use of these medications that are giving those the Ozempic face and the Ozempic breast and the Ozempic butt."

The average recommended weight loss is around "1 to 2 pounds a week", which will allow the skin to bounce back as the body gradually shrinks.

To avoid a saggy butt, Saleh recommended: "Increase of protein in their diet is very important. Increase of exercise, resistance bands.

"In terms of the buttocks, [do] more squats, more to increase muscle to compensate really for the fat loss."

And it's not just the aesthetics that Ozempic can have an effect on, as some women who were previously struggling to conceive have found they have fallen pregnant after taking Ozempic.

Saleh explained that there is a scientific reason for it, revealing: "Even if it's a 5- or 10-pound weight loss, this can actually have patients resume ovulation and be able to get pregnant.

"Our fat cells produce estrogen and estrogen can have a negative effect on our ovaries in terms of decreased or dysfunction of ovulation. It can also have negative effects on our endometrial lining."

And while the weight loss can aid conception, Ozempic is not a fertility drug and should also not be used during pregnancy, with manufacturer Novo Nordisk (which creates a similar product named Wegovy), recommending it's stopped "at least 2 months before a planned pregnancy due to the long washout period for semaglutide."

And, as with most 'quick fixes' for weight loss, there's a high chance of a person regaining all the weight they lost once they stop taking it, if they haven't changed their eating or exercise habits alongside it.

Featured image credit: Mario Tama/Getty Images

As summer rapidly approaches, some people will be trying to get their body ready for the beach... but one thing stressing them out is "Ozempic butt".

Yep, it turns out that the viral weight-loss drug Ozempic — originally developed for managing Type 2 diabetes — is now leaving users with more than just a smaller waistline.

Rapid weight loss is transforming butts, faces, and even boobs in unexpected (and unwanted) ways.

Let’s get this out of the way first: Ozempic isn’t a weight loss drug. It even states that on the official Ozempic website.

It is a medication for adults with type 2 diabetes to “improve blood sugar (glucose)” and “reduce the risk of major cardiovascular events such as heart attack, stroke, or death.”

While dramatic weight loss is the point for many users, the aftermath isn’t always glamorous.

Meet 'Ozempic butt', the term now making waves online.

Jess Loren, 39, shared her experience with the New York Post after dropping over 75lb with Ozempic: “My dad said, ‘You don’t have a butt anymore.’ I try on bathing suits and I’ve got 'ghost a**,' or what people online call 'Ozempic butt.'”

It’s not an officially listed side-effect, but rapid weight loss can cause skin in once-plump areas to sag. And butts aren’t the only victims.

Many celebrities have also reportedly fallen victim to ‘Ozempic face,’ where cheeks hollow out and eyes look sunken.

Dr. Iman Saleh, Director of Obesity Medicine at South Shore University Hospital, explained to PEOPLE: “The faces are saggy, they lose their fat content in their face, there are increased wrinkles.

"Some people look a little bit more aged. People have noticed that there's more hollowing around their eyes because of the loss of the texture or the fat content that is in the face.”

Same goes for breasts.

Saleh continued: “People who have had weight-loss surgeries will have the same effect. So, it's not the medications itself that are causing this. It's the rapid weight loss that is occurring with the use of these medications that are giving those the Ozempic face and the Ozempic breast and the Ozempic butt.”

Her advice is to take it slow.

The recommended rate of weight loss is “one to two pounds a week” to give your skin time to bounce back.

And if you're trying to keep your curves: “Increase of protein in their diet is very important. Increase of exercise, resistance bands. In terms of the buttocks, [do] more squats, more to increase muscle to compensate really for the fat loss.”

In case you need a more visual idea of what Ozempic does, then Zack D. Films is the man for you.

As he put it in his now-viral simulation: “Once Ozempic is in your bloodstream, it activates the parts of the brain that make you feel full, reducing your appetite. It also stabilises your blood sugar, stopping sudden cravings.

"Then it slows down how fast your stomach empties food, which keeps you feeling full for longer after a meal. This causes you to lose weight as you eat less. But it can make some people feel sick and even give them diarrhoea.”

Lovely.

Featured image credit: Mario Tama/Getty Images

Experts have raised an urgent alert about a potential side effect linked to widely used drugs like Ozempic and Mounjaro.

The drug that has been credited with transforming the world of weight loss by nullifying the cravings of those looking to shed the pounds, was originally introduced as a treatment for type 2 diabetes to help reduce and regulate blood sugar levels.

While semaglutide, which comes under the brand name Ozempic, is yet to receive FDA approval for treatment-targeted weight loss, its competitor, Mounjaro, has been in receipt of formal FDA-verification as a treatment for obesity and weight loss, as well as for its initial purpose.

What have experts discovered?

However, in a recent development, scientists have cited a potential increase in risk of certain kinds of vision loss in people with type 2 diabetes.

Credit: coldsnowstorm / Getty

Researchers at the University of Toronto have now found that GLP‑1 drugs, a class that includes both Ozempic and Mounjaro, are associated with a considerably higher risk of developing neovascular age‑related macular degeneration (AMD), a serious eye condition.

Their study suggests that people with type 2 diabetes prescribed these drugs were more than twice as likely to develop vision problems compared with those taking the same medications who did not have diabetes.

What is Neovascular AMD?

Neovascular AMD, often simply called AMD, is described by the NHS as “a common condition that affects the middle part of your vision,” and Healthline notes that it is a leading cause of irreversible vision loss in people over 50 in the United States.

Commenting on the findings, co‑author Andrew Mihalache, MD(C), said: “The dose-response effect we observed — where longer GLP-1 receptor agonist exposure was associated with higher risk — strengthens the argument that this association may reflect a true biological effect rather than being due to confounding factors.”

Fellow author Reut Shor, MD, added: “This was definitely surprising, especially given the growing enthusiasm for GLP-1 receptor agonists for their cardiovascular and metabolic benefits. It really highlights the need for further investigation into their ocular safety profile.”

Despite these concerns, the overall risk of vision loss from taking GLP‑1 drugs such as Ozempic and Mounjaro remains very low: with the study estimating the risk of developing AMD at about 0.2 percent among the respective treatments' users.

If you are thinking about starting a GLP‑1 medication, it is essential to speak with a healthcare professional to discuss whether this treatment is suitable and safe for you.

Featured Image. Credit: coldsnowstorm / Getty